Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953068 | 1.00 | TP53 (0.43) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| Ammonia Solution, Strong SCHEMBL2359960 | 0.98 | TP53 (0.42) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL5543322 | 0.83 | GAA (0.47) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL15200264 | 0.83 | GAA (0.47) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL17118123 | 0.83 | TP53 (0.46) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL358775 | 0.83 | GAA (0.47) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL14305169 | 0.83 | TP53 (0.46) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL2948892 | 0.82 | TP53 (0.56) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 | |
| SCHEMBL244740 | 0.82 | — | — | |
| SCHEMBL2200767 | 0.82 | TP53 (0.56) | TP53ALDH1A1GAASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039921-A1 | ANTIFIBRINOLYTIC COMPOUNDS | CHIBBER BAKSHY A (US) | 2020-02-06 | — | — | US | disclosed |
| US-10202331-B2 | Antifibrinolytic compounds | THROMBOLYTICS LLC (US) | 2019-02-12 | — | — | US | disclosed |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | THROMBOLYTICS, LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | THROMBOLYTICS, LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202331-B2 | Antifibrinolytic compounds | F2, FGB, SERPINC1 | TP53 2911/4885ALDH1A1 3804/4885GAA 2471/4885 |
| US-20170334834-A1 | ANTIFIBRINOLYTIC COMPOUNDS | F2, SERPINC1, F12 | TP53 4854/4885ALDH1A1 930/4885GAA 1446/4885 |
| US-20200039921-A1 | ANTIFIBRINOLYTIC COMPOUNDS | F2, SERPINC1, F12 | TP53 4854/4885ALDH1A1 930/4885GAA 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.