Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877225 | 0.87 | GABRA1 (0.46) | MAPK1ESR1ESR2GABRA1GABRB2 | |
| SCHEMBL14154535 | 0.83 | MAPT (0.42) | SHBGMAPTMAPK1L3MBTL1NPSR1 | |
| SCHEMBL836394 | 0.83 | CA1 (0.50) | MAPTMAPK1L3MBTL1ESR1ESR2 | |
| SCHEMBL14011317 | 0.81 | MAPT (0.41) | SHBGMAPTMAPK1L3MBTL1NPSR1 | |
| SCHEMBL28174120 | 0.75 | BRD4 (0.38) | MAPTMAPK1L3MBTL1NPSR1ESR1 | |
| SCHEMBL13678595 | 0.75 | ALDH1A1 (0.35) | SHBGMAPTMAPK1GABRA1GABRB2 | |
| SCHEMBL9749694 | 0.74 | CA1 (0.59) | SHBGMAPTESR1ESR2GABRA1 | |
| SCHEMBL70083 | 0.74 | CYP3A4 (0.42) | SHBGESR1ESR2GABRA1GABRB2 | |
| SCHEMBL1021767 | 0.74 | ALDH1A1 (0.48) | SHBGMAPTMAPK1L3MBTL1ESR1 | |
| SCHEMBL31028130 | 0.74 | CA1 (0.59) | SHBGMAPTESR1ESR2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335087-A1 | Method for providing resistance to yellowing in polyamide articles and polyamide articles obtained from this method | RHODIA POLIAMIDA E ESPECIALIDADES LTDA (BR) | 2017-11-23 | — | — | US | disclosed |