Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028130 | 1.00 | CA1 (0.59) | CA1CA2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30250589 | 1.00 | CA1 (0.59) | CA1CA2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1023493 | 0.88 | PTPN1 (0.49) | CA1CA2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5023947 | 0.85 | GABRA1 (0.55) | CA1CA2CYP1A2CYP2C9ESR1 | |
| SCHEMBL11612512 | 0.82 | CA1 (0.54) | CA1CA2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1021767 | 0.81 | ALDH1A1 (0.48) | CA1CA2CYP2C9CYP2C19SHBG | |
| SCHEMBL70083 | 0.81 | CYP3A4 (0.42) | CA1CA2CYP1A2CYP2C9SHBG | |
| SCHEMBL30576381 | 0.81 | ALDH1A1 (0.48) | CA1CA2CYP2C9CYP2C19SHBG | |
| SCHEMBL27647441 | 0.80 | ESR1 (0.44) | CA1CA2CYP1A2CYP2C9SHBG | |
| SCHEMBL31092543 | 0.79 | SHBG (0.55) | CA1CA2SHBGESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2023-05-18 | — | — | US | claimed |
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | ORPHA BIOTECH S.R.L. (IT) | 2023-05-18 | — | — | US | disclosed |
| US-5171891-A | Using sulfur containing oxy acids and their salts | ALLIED-SIGNAL INC. (US) | 1992-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149323-A1 | INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS | FPR3, FPR1, PLAUR | CA1 4645/4885CA2 4714/4885CYP1A2 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.