SCHEMBL19626175

SCHEMBL19626175

C=CC(=O)OCCCc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.52
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.51
THRB P10828 7/20 0.51
CTDSP1 Q9GZU7 1/20 0.50
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
APOBEC3A P31941 1/20 0.49
APOBEC3G Q9HC16 1/20 0.49
TP53 P04637 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRA P10827 4/20 0.44
AKR1B10 O60218 2/20 0.43
AKR1B1 P15121 2/20 0.43
MET P08581 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13839894 0.92 THRB (0.48) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL1628452 0.92 THRB (0.48) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL144962 0.90 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL12173362 0.90 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL14588414 0.90 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL5032103 0.88 THRB (0.45) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL21880707 0.88 THRB (0.45) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL15726793 0.88 THRB (0.45) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL1630809 0.87 THRB (0.50) TSHRALDH1A1CYP3A4HPGDTHRB
SCHEMBL28380935 0.87 THRB (0.64) TSHRALDH1A1CYP3A4HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10642119-B2 Electrochromic compound, electrochromic composition, and electrochromic element RICOH COMPANY, LTD. (JP) 2020-05-05 US disclosed
US-20170336691-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-23 US disclosed
US-20170336691-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-23 US disclosed