Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962776 | 0.94 | MAOB (0.52) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL4689393 | 0.85 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10044351 | 0.82 | NPC1 (0.60) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL18526953 | 0.82 | NPC1 (0.45) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL1630447 | 0.81 | NR4A1 (0.68) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10432798 | 0.81 | MAPT (0.50) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL22668280 | 0.80 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL657234 | 0.80 | TDP1 (0.55) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL9653413 | 0.80 | NPC1 (0.65) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL18526954 | 0.79 | MAOB (0.56) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563599-B2 | Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110144195-A1 | METHODS FOR SYNTHESIZING GLYCINOLS, GLYCEOLLINS I AND II, COMPOSITIONS OF SELECTED INTERMEDIATES, AND THERAPEUTIC USES THEREOF | XAVIER UNIVERSITY OF LOUISIANA | 2011-06-16 | — | — | US | disclosed |
| WO-2009111428-A2 | METHODS FOR SYNTHESIZING GLYCINOLS, GLYCEOLLINS I AND II, COMPOSITIONS OF SELECTED INTERMEDIATES, AND THERAPEUTIC USES THEREOF | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2009-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144195-A1 | METHODS FOR SYNTHESIZING GLYCINOLS, GLYCEOLLINS I AND II, COMPOSITIONS OF SELECTED INTERMEDIATES, AND THERAPEUTIC USES THEREOF | GPER1, ESR2, GNE | SMN1; SMN2 3213/4885RAB9A 4472/4885NPC1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.