SCHEMBL19628141

SCHEMBL19628141

c1ccc(N(c2ccccc2)c2ccc(-c3cc4cccc5c6c7ccccc7sc6c6cccc3c6c45)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
APP P05067 1/20 0.33
TNKS O95271 2/20 0.32
TNKS2 Q9H2K2 2/20 0.32
GPR84 Q9NQS5 1/20 0.31
PTPN1 P18031 1/20 0.30
F9 P00740 1/20 0.30
ELANE P08246 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
MPI P34949 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19628140 0.88 MEN1 (0.38) ALOX5TNKSTNKS2GPR84PTPN1
SCHEMBL14882843 0.86 ALOX5 (0.39) ALOX5APPTNKSTNKS2GPR84
SCHEMBL19628174 0.86 GPR84 (0.32) GPR84
SCHEMBL14725663 0.85 ALOX5 (0.39) ALOX5APPTNKSTNKS2GPR84
SCHEMBL24888760 0.85 GPR84 (0.36) ALOX5APPTNKSTNKS2GPR84
SCHEMBL19628185 0.85 ALOX5 (0.41) ALOX5TNKSTNKS2F9ALDH1A1
SCHEMBL25881157 0.85 GPR84 (0.36) ALOX5APPTNKSTNKS2GPR84
SCHEMBL14961985 0.84 ALDH1A1 (0.40) APPGPR84KDM4EMEN1ALDH1A1
SCHEMBL19628178 0.84 MEN1 (0.35) ALOX5TNKSTNKS2GPR84PTPN1
SCHEMBL15197364 0.83 ALDH1A1 (0.39) APPGPR84KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439144-B2 Organic compound for electronic device comprising fused-core structure, organic optoelectronic device comprising same, and display device UNIVERSITY-INDUSTRY COOPERATEON GROUP OF KYUNG HEE UNIVERSITY (KR) 2019-10-08 US disclosed
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-11-23 US disclosed
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439144-B2 Organic compound for electronic device comprising fused-core structure, organic optoelectronic device comprising same, and display device OR10J3, OCIAD2, OCIAD1 ALOX5 1129/4885APP 464/4885TNKS 4514/4885
US-20170338416-A1 ORGANIC COMPOUND FOR ELECTRONIC DEVICE COMPRISING FUSED-CORE STRUCTURE, ORGANIC OPTOELECTRONIC DEVICE COMPRISING SAME, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALOX5 1129/4885APP 464/4885TNKS 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.