Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628264 | 0.88 | HIF1A (0.52) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL19628267 | 0.85 | HIF1A (0.51) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL25039850 | 0.73 | HIF1A (0.49) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL16153735 | 0.72 | CYP2C19 (0.53) | HIF1ACYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL20810448 | 0.71 | CYP2D6 (0.43) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL20810369 | 0.69 | CYP2C19 (0.41) | HIF1ACYP1A2CYP2C19CYP2C9TSHR | |
| SCHEMBL8352502 | 0.69 | HIF1A (0.53) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL14804453 | 0.68 | ALOX5 (0.43) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL14883383 | 0.67 | ALOX5 (0.45) | HIF1AALOX5PTGS2CYP1A2CYP2C19 | |
| SCHEMBL17656826 | 0.67 | ALOX5 (0.45) | HIF1AALOX5PTGS2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335061-A1 | ISOTACTIC POLYETHERS AND BIMETALLIC CATALYSTS, METHODS OF MAKING SAME, AND USES THEREOF | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170335061-A1 | ISOTACTIC POLYETHERS AND BIMETALLIC CATALYSTS, METHODS OF MAKING SAME, AND USES THEREOF | SQLE, PAOX, AGL | HIF1A 4222/4885ALOX5 10/4885PTGS2 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.