Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.46 |
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10173679 | 0.85 | PRCP (0.45) | PRCPHPGDS | |
| SCHEMBL19628290 | 0.83 | PRKCZ (0.36) | PRCPHPGDS | |
| SCHEMBL10254958 | 0.81 | PRCP (0.54) | PRCPHPGDSGPR119 | |
| SCHEMBL12599425 | 0.79 | PRCP (0.53) | PRCPHPGDS | |
| SCHEMBL10219378 | 0.79 | PRCP (0.45) | PRCPHPGDS | |
| SCHEMBL10076571 | 0.79 | PRCP (0.59) | PRCPHPGDS | |
| SCHEMBL10257868 | 0.79 | PRCP (0.54) | PRCPHPGDSGPR119 | |
| SCHEMBL16378620 | 0.77 | PRCP (0.51) | PRCPHPGDS | |
| SCHEMBL7604141 | 0.77 | PRCP (0.55) | PRCPHPGDS | |
| SCHEMBL6126817 | 0.77 | PRCP (0.55) | PRCPHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065985-A1 | PROCESS FOR MAKING TETRACYCLIC HETEROCYCLE COMPOUNDS | MERCK SHARPE & DOHME CORP. (US) | 2018-03-08 | — | — | US | disclosed |
| US-20170334926-A1 | PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334926-A1 | PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS | IDO1, IDO2, TPH1 | PRCP 2028/4885HPGDS 2744/4885GPR119 527/4885 |
| US-20180065985-A1 | PROCESS FOR MAKING TETRACYCLIC HETEROCYCLE COMPOUNDS | CYP1B1, CYP1A2, CYP2F1 | PRCP 362/4885HPGDS 521/4885GPR119 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.