Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 9/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628289 | 0.83 | PRCP (0.46) | PRCPHPGDS | |
| SCHEMBL10173681 | 0.80 | SSTR3 (0.34) | — | |
| SCHEMBL903540 | 0.74 | SSTR3 (0.30) | — | |
| SCHEMBL19628293 | 0.73 | PRKCZ (0.38) | PRKCZ | |
| SCHEMBL19929298 | 0.73 | GAA (0.41) | PRKCZ | |
| SCHEMBL903797 | 0.72 | NR1H4 (0.31) | — | |
| SCHEMBL12175267 | 0.71 | GCGR (0.39) | PRCPPLATHPGDSGCGR | |
| SCHEMBL1746986 | 0.69 | PRCP (0.53) | PRCP | |
| SCHEMBL13291653 | 0.69 | ADORA2A (0.46) | — | |
| SCHEMBL17613189 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065985-A1 | PROCESS FOR MAKING TETRACYCLIC HETEROCYCLE COMPOUNDS | MERCK SHARPE & DOHME CORP. (US) | 2018-03-08 | — | — | US | disclosed |
| US-20170334926-A1 | PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334926-A1 | PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS | IDO1, IDO2, TPH1 | PRKCZ 4391/4885PRCP 2028/4885PLAT 4683/4885 |
| US-20180065985-A1 | PROCESS FOR MAKING TETRACYCLIC HETEROCYCLE COMPOUNDS | CYP1B1, CYP1A2, CYP2F1 | PRKCZ 4187/4885PRCP 362/4885PLAT 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.