Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628373 | 0.85 | MAPT (0.39) | MAPTMEN1KMT2ACYP2C19CYP2C9 | |
| SCHEMBL19614767 | 0.82 | LTA4H (0.41) | MEN1KMT2ARCE1HTTALDH1A1 | |
| SCHEMBL19614764 | 0.82 | LTA4H (0.41) | MEN1KMT2ARCE1HTTALDH1A1 | |
| SCHEMBL19633669 | 0.82 | LTA4H (0.41) | MEN1KMT2ARCE1HTTALDH1A1 | |
| SCHEMBL16177521 | 0.81 | SLC1A3 (0.41) | MAPTSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL22490419 | 0.81 | SLC1A3 (0.42) | MAPTSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL22490420 | 0.81 | SLC1A3 (0.42) | MAPTSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7949742 | 0.77 | TSHR (0.42) | MAPTSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL18747098 | 0.75 | TSHR (0.44) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL76044 | 0.74 | TSHR (0.61) | KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | MAPT 1596/4885SLC1A3 1688/4885SLC1A2 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.