Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628419 | 0.94 | TP53 (0.34) | KMT2AL3MBTL1NAAAMEN1CYP1A2 | |
| SCHEMBL19628394 | 0.94 | SCN9A (0.37) | KMT2AL3MBTL1NAAAKDM1AMAOB | |
| SCHEMBL19628408 | 0.91 | KDM1A (0.36) | KMT2AL3MBTL1NAAAKDM1AMAOB | |
| SCHEMBL19628402 | 0.88 | REN (0.37) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL17427146 | 0.87 | KMT2A (0.40) | KMT2AL3MBTL1NAAA | |
| SCHEMBL19628393 | 0.87 | KMT2A (0.36) | KMT2AL3MBTL1NAAA | |
| SCHEMBL16605405 | 0.85 | KMT2A (0.43) | KMT2AL3MBTL1NAAAKDM1AMAOB | |
| SCHEMBL17898805 | 0.85 | KMT2A (0.41) | KMT2AL3MBTL1NAAAKDM1AMAOB | |
| SCHEMBL17760967 | 0.83 | KMT2A (0.35) | KMT2ANAAAMEN1CYP1A2 | |
| SCHEMBL19628421 | 0.82 | GAA (0.33) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | KMT2A 3234/4885L3MBTL1 3973/4885NAAA 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.