Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628421 | 0.91 | GAA (0.33) | KDM1AGAA | |
| SCHEMBL19628397 | 0.91 | KMT2A (0.38) | KDM1AMAOBKMT2AL3MBTL1NAAA | |
| SCHEMBL19628402 | 0.89 | REN (0.37) | KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19628394 | 0.87 | SCN9A (0.37) | KDM1AMAOBKMT2AL3MBTL1NAAA | |
| SCHEMBL19628419 | 0.87 | TP53 (0.34) | KDM1AMAOBKMT2AL3MBTL1NAAA | |
| SCHEMBL16604078 | 0.84 | KMT2A (0.40) | KDM1AMAOBKMT2AL3MBTL1GAA | |
| SCHEMBL16605392 | 0.82 | KMT2A (0.41) | KDM1AMAOBKMT2AL3MBTL1GAA | |
| SCHEMBL17898871 | 0.82 | GAA (0.39) | KDM1AMAOBKMT2AL3MBTL1GAA | |
| SCHEMBL17898879 | 0.82 | GAA (0.39) | KDM1AMAOBKMT2AL3MBTL1GAA | |
| SCHEMBL17898811 | 0.82 | GAA (0.38) | KDM1AMAOBKMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | KDM1A 1840/4885MAOB 2013/4885KMT2A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.