SCHEMBL1962841

SCHEMBL1962841

CCC1=C(N)C(=O)NC1=O

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.30
▸ GRIN3B O60391 1/20 0.30
▸ GRIN1 Q05586 1/20 0.30
▸ GRIN2A Q12879 1/20 0.30
▸ GRIN2B Q13224 1/20 0.30
▸ GRIN2C Q14957 1/20 0.30
▸ GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988700 0.81 LMNA (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8733759 0.71 — —
SCHEMBL890999 0.70 XIAP (0.39) —
SCHEMBL4384017 0.70 NPSR1 (0.33) —
SCHEMBL2126262 0.67 MAPT (0.31) —
Triethylene Glycol SCHEMBL5699200 0.64 MEN1 (0.46) —
SCHEMBL17226003 0.62 — —
SCHEMBL8333111 0.62 GSK3B (0.58) —
SCHEMBL29150779 0.61 TP53 (0.43) —
SCHEMBL9491519 0.58 XIAP (0.40) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10989651-B2 Molecular detection system THE UNIVERSITY OF BIRMINGHAM (GB) 2021-04-27 — — US disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 — — EP disclosed
CN-110204478-A Carbonic anhydrase targeting agent and its application method 文森医学公司 2019-09-06 — — CN disclosed
EP-3149451-B1 IMPROVED MOLECULAR DETECTION SYSTEM UNIV BIRMINGHAM (GB) 2019-02-20 — — EP disclosed
CN-104955484-B Prostate-specific antigen medicament and its application method for prostate cancer imaging 文森医学公司 2019-01-15 — — CN disclosed
US-20170191927-A1 IMPROVED MOLECULAR DETECTION SYSTEM THE UNIVERSITY OF BIRMINGHAM (GB) 2017-07-06 — — US disclosed
EP-3149451-A1 IMPROVED MOLECULAR DETECTION SYSTEM The University Of Birmingham (GB) 2017-04-05 — — EP disclosed
US-20160368993-A1 ALPHA-V BETA-6 INTEGRIN-BINDING ANTIBODY FRAGMENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-12-22 — — US disclosed
WO-2015181546-A1 IMPROVED MOLECULAR DETECTION SYSTEM THE UNIVERSITY OF BIRMINGHAM (GB) 2015-12-03 — — WO disclosed
US-9175036-B2 Antimicrobial water treatment membranes and production thereof BEN-GURION UNVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2015-11-03 — — US disclosed
EP-1535952-B1 Method for preparing crosslinked polyelectrolyte multilayer films UNIV PASTEUR (FR) 2013-01-16 — — EP disclosed
US-20120325748-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF BAR-ILAN UNIVERSITY (IL) 2012-12-27 — — US disclosed
WO-2012172547-A1 IMMOBILIZATION OF ANTIMICROBIAL POLYMERS ON RO MEMBRANE TO REDUCE BIOFILM GROWTH AND BIOFOULING BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2012-12-20 — — WO disclosed
EP-2509614-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF Ben-Gurion University Of The Negev Research And Development Authority (IL) 2012-10-17 — — EP disclosed
WO-2011070573-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2011-06-16 — — WO disclosed
US-20070129792-A1 Method for preparing crosslinked polyelectrolyte multilayer films INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2007-06-07 — — US disclosed
CN-1307263-C Fluorescent dye, method and kit for saturation labeling of proteins AMOSEN BIOLOG SCIENCE BRITISH (GB) 2007-03-28 — — CN disclosed
CN-1650168-A Reagents and methods for saturation labelling of proteins AMOSEN BIOLOG SCIENCE BRITISH (GB) 2005-08-03 — — CN disclosed
WO-2005052035-A1 METHOD FOR PREPARING CROSSLINKED POLYELECTROLYTE MULTILAYER FILMS UNIVERSITE LOUIS PASTEUR (FR) 2005-06-09 — — WO disclosed
EP-1535952-A1 Method for preparing crosslinked polyelectrolyte multilayer films UNIVERSITE LOUIS PASTEUR (FR) 2005-06-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120325748-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF AQP1, VIP, AQP3 GRIN2D 4296/4885GRIN3B 4132/4885GRIN1 4122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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