SCHEMBL1962841

SCHEMBL1962841

CCC1=C(N)C(=O)NC1=O

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988700 0.81 LMNA (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8733759 0.71
SCHEMBL890999 0.70 XIAP (0.39)
SCHEMBL4384017 0.70 NPSR1 (0.33)
SCHEMBL2126262 0.67 MAPT (0.31)
Triethylene Glycol SCHEMBL5699200 0.64 MEN1 (0.46)
SCHEMBL17226003 0.62
SCHEMBL8333111 0.62 GSK3B (0.58)
SCHEMBL29150779 0.61 TP53 (0.43)
SCHEMBL9491519 0.58 XIAP (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10989651-B2 Molecular detection system THE UNIVERSITY OF BIRMINGHAM (GB) 2021-04-27 US disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP disclosed
CN-110204478-A Carbonic anhydrase targeting agent and its application method 文森医学公司 2019-09-06 CN disclosed
EP-3149451-B1 IMPROVED MOLECULAR DETECTION SYSTEM UNIV BIRMINGHAM (GB) 2019-02-20 EP disclosed
CN-104955484-B Prostate-specific antigen medicament and its application method for prostate cancer imaging 文森医学公司 2019-01-15 CN disclosed
US-20170191927-A1 IMPROVED MOLECULAR DETECTION SYSTEM THE UNIVERSITY OF BIRMINGHAM (GB) 2017-07-06 US disclosed
EP-3149451-A1 IMPROVED MOLECULAR DETECTION SYSTEM The University Of Birmingham (GB) 2017-04-05 EP disclosed
US-20160368993-A1 ALPHA-V BETA-6 INTEGRIN-BINDING ANTIBODY FRAGMENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-12-22 US disclosed
WO-2015181546-A1 IMPROVED MOLECULAR DETECTION SYSTEM THE UNIVERSITY OF BIRMINGHAM (GB) 2015-12-03 WO disclosed
US-9175036-B2 Antimicrobial water treatment membranes and production thereof BEN-GURION UNVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2015-11-03 US disclosed
EP-1535952-B1 Method for preparing crosslinked polyelectrolyte multilayer films UNIV PASTEUR (FR) 2013-01-16 EP disclosed
US-20120325748-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF BAR-ILAN UNIVERSITY (IL) 2012-12-27 US disclosed
WO-2012172547-A1 IMMOBILIZATION OF ANTIMICROBIAL POLYMERS ON RO MEMBRANE TO REDUCE BIOFILM GROWTH AND BIOFOULING BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2012-12-20 WO disclosed
EP-2509614-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF Ben-Gurion University Of The Negev Research And Development Authority (IL) 2012-10-17 EP disclosed
WO-2011070573-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2011-06-16 WO disclosed
US-20070129792-A1 Method for preparing crosslinked polyelectrolyte multilayer films INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2007-06-07 US disclosed
CN-1307263-C Fluorescent dye, method and kit for saturation labeling of proteins AMOSEN BIOLOG SCIENCE BRITISH (GB) 2007-03-28 CN disclosed
CN-1650168-A Reagents and methods for saturation labelling of proteins AMOSEN BIOLOG SCIENCE BRITISH (GB) 2005-08-03 CN disclosed
WO-2005052035-A1 METHOD FOR PREPARING CROSSLINKED POLYELECTROLYTE MULTILAYER FILMS UNIVERSITE LOUIS PASTEUR (FR) 2005-06-09 WO disclosed
EP-1535952-A1 Method for preparing crosslinked polyelectrolyte multilayer films UNIVERSITE LOUIS PASTEUR (FR) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120325748-A1 ANTIMICROBIAL WATER TREATMENT MEMBRANES AND PRODUCTION THEREOF AQP1, VIP, AQP3 GRIN2D 4296/4885GRIN3B 4132/4885GRIN1 4122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.