SCHEMBL19628566

SCHEMBL19628566

CCc1cc(CCCCCCCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.60
GAA P10253 5/20 0.50
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 6/20 0.46
MEN1 O00255 4/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
HIF1A Q16665 3/20 0.46
MAPT P10636 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
ATM Q13315 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
USP2 O75604 1/20 0.46
CYP2D6 P10635 1/20 0.46
LMNA P02545 3/20 0.46
RECQL P46063 1/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25424133 0.94 HSPA5 (0.57) HSPA5GAAKMT2AALDH1A1HIF1A
SCHEMBL10605938 0.92 HSPA5 (0.55) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL19623215 0.89 HSPA5 (0.51) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL2916112 0.89 HSPA5 (0.58) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL3762751 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL18193748 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL8751545 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL8751548 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL17588977 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1
SCHEMBL18193749 0.88 ALDH1A1 (0.57) HSPA5GAAKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301544-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2019-05-28 US disclosed
US-20170335195-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-11-23 US disclosed
US-20170335195-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-11-23 US disclosed