SCHEMBL2916112

SCHEMBL2916112

CCc1cc(CCCO)cc(C(C)(C)C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.58
GAA P10253 5/20 0.46
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 3/20 0.44
MAPT P10636 3/20 0.44
GSR P00390 2/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 4/20 0.44
LMNA P02545 4/20 0.44
HIF1A Q16665 3/20 0.44
MEN1 O00255 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10605938 0.94 HSPA5 (0.55) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL3809095 0.90 HSPA5 (0.62) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL14002951 0.89 HSPA5 (0.65) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL19628566 0.89 HSPA5 (0.60) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL2910785 0.88 HSPA5 (0.44) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL2917130 0.86 HSPA5 (0.43) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL2414760 0.86 ALDH1A1 (0.56) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL25424133 0.86 HSPA5 (0.57) HSPA5GAAKMT2AALDH1A1KDM4E
SCHEMBL28747943 0.86 HSPA5 (0.49) HSPA5GAAKMT2AALDH1A1MAPK1
SCHEMBL14003051 0.86 HSPA5 (0.61) HSPA5GAAKMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
CN-1572795-A Process for producing phosphite SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed
EP-0171139-B1 HIGH POLYMER STABILIZER CONTAINING A PHENOLIC COMPOUND, AND HIGH POLYMERS STABILIZED THEREBY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-26 EP disclosed
EP-0171139-A2 High polymer stabilizer containing a phenolic compound, and high polymers stabilized thereby SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 HSPA5 860/4885GAA 4341/4885KMT2A 3167/4885
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 HSPA5 4485/4885GAA 3798/4885KMT2A 3796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.