SCHEMBL196299

SCHEMBL196299

CCC(=O)c1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.64
L3MBTL1 Q9Y468 4/20 0.57
MAPT P10636 3/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17187853 1.00 GSK3B (0.64) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
SCHEMBL7214228 1.00 GSK3B (0.64) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
SCHEMBL11305427 0.94 L3MBTL1 (0.68) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
Acetic Acid SCHEMBL27667375 0.94 GSK3B (0.57) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
SCHEMBL27759976 0.92 GSK3B (0.55) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
Paroxypropione SCHEMBL27862463 0.92 NPC1 (0.65) GSK3BL3MBTL1MAPTSMN1; SMN2NPC1
SCHEMBL11780135 0.90 GSK3B (0.57) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5
SCHEMBL6142809 0.88 MMP1 (0.59) GSK3BL3MBTL1MAPTSMN1; SMN2NPC1
SCHEMBL8051337 0.87 SMN1; SMN2 (0.70) GSK3BL3MBTL1MAPTSMN1; SMN2NPC1
Fluorobenzene SCHEMBL27628207 0.85 MAPT (0.58) GSK3BL3MBTL1MAPTSMN1; SMN2ERCC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240091111-A1 METHODS OF MASKING OFF-TASTES GIVAUDAN SA (CH) 2024-03-21 US claimed
EP-4297716-A1 METHODS OF MASKING OFF-TASTES Givaudan SA (CH) 2024-01-03 EP claimed
CN-111574569-B Coordination compound of rhodium, preparation method and application thereof 安徽师范大学 2023-04-18 CN claimed
WO-2022180141-A1 METHODS OF MASKING OFF-TASTES GIVAUDAN SA (CH) 2022-09-01 WO claimed
CN-212605364-U Conveyer is used in processing of p-chlorophenylacetone 襄阳市宇爵化工有限公司 2021-02-26 CN claimed
CN-111574569-A Coordination compound of rhodium, preparation method and application thereof 安徽师范大学 2020-08-25 CN claimed
CN-101500996-B (3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives ACTELION PHARMACEUTICALS LTD 2012-07-04 CN claimed
WO-2008056377-A2 POLYMORPHIC FORMS OF RIMONABANT CADILA HEALTHCARE LIMITED (IN) 2008-05-15 WO claimed
EP-0107198-B1 USE OF 2-HYDROXY-2-METHYL-(P-CHLOROPROPIONPHENONE) AS A PHOTOINITIATOR CIBA-GEIGY AG (CH) 1987-07-08 EP claimed
US-3956153-A MINIMIZATION OF UNDERCOOLING BIO-MEDICAL SCIENCES, INC. (US) 1976-05-11 US claimed
JP-10087490-A None JP disclosed
WO-2025215121-A1 HEDGEHOG ACYLTRANSFERASE INHIBITORS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-10-16 WO disclosed
US-12281058-B2 Manganese catalysts and their use in hydrogenation of ketones UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2025-04-22 US disclosed
CN-119390551-A Method for realizing methoxymethylation under photocatalysis condition 浙江工业大学 2025-02-07 CN disclosed
US-20250042831-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2025-02-06 US disclosed
US-4009157-A POLYESTER FOAMING AGENTS, FREE RADICAL CATALYSTS PENNWALT CORPORATION (US) 1977-02-22 US disclosed
US-3980581-A NUCLEATING AGENTS, SOLID SOLUTIONS BIO-MEDICAL SCIENCES, INC. (US) 1976-09-14 US disclosed
US-3956153-A MINIMIZATION OF UNDERCOOLING BIO-MEDICAL SCIENCES, INC. (US) 1976-05-11 US disclosed
US-3956316-A PROGESTATIONAL AND SALT-RETAINING AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-05-11 US disclosed
US-3946612-A Temperature indicating compositions BIO-MEDICAL SCIENCES, INC. (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12281058-B2 Manganese catalysts and their use in hydrogenation of ketones CYC1, SCO2, MT-CO3 GSK3B 3681/4885L3MBTL1 1159/4885MAPT 4683/4885
US-20250042831-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE SI, IDO1, CYP4B1 GSK3B 1400/4885L3MBTL1 4742/4885MAPT 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.