SCHEMBL19629960

SCHEMBL19629960

O=C1COc2c(F)cc(S)cc2N1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 11/20 0.45
PGR P06401 6/20 0.45
NR3C1 P04150 4/20 0.45
PARP1 P09874 2/20 0.39
MMP12 P39900 1/20 0.38
PDE3B Q13370 2/20 0.38
PDE3A Q14432 2/20 0.38
HTR1A P08908 2/20 0.38
DRD2 P14416 2/20 0.38
HTR2A P28223 2/20 0.38
ADRB2 P07550 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705085 0.83 NR3C2 (0.50) NR3C2PGRNR3C1MMP12PDE3B
SCHEMBL8202873 0.80 NR3C2 (0.45) NR3C2PGRNR3C1PARP1MMP12
SCHEMBL12116980 0.80 PDE3B (0.53) NR3C2PGRNR3C1PARP1MMP12
SCHEMBL21372202 0.80 NR3C2 (0.48) NR3C2PGRNR3C1PARP1MMP12
SCHEMBL29939223 0.80 NR3C2 (0.45) NR3C2PGRNR3C1PARP1MMP12
SCHEMBL21552373 0.80 PGR (0.45) NR3C2PGRNR3C1MMP12PDE3B
SCHEMBL4102483 0.80 NR3C2 (0.45) NR3C2PGRNR3C1PARP1MMP12
SCHEMBL3276712 0.78 NR3C2 (0.44) NR3C2PGRNR3C1MMP12PDE3B
SCHEMBL29952529 0.78 NR3C2 (0.44) NR3C2PGRNR3C1MMP12PDE3B
SCHEMBL5258793 0.76 NR3C2 (0.43) NR3C2PGRNR3C1MMP12PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711011-B2 Substituted oxazolidines as anti-bacterial agents Bugworks Research, Inc. (US) 2020-07-14 US disclosed
WO-2017199265-A1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION BUGWORKS RESEARCH INDIA PVT LTD (IN) 2017-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711011-B2 Substituted oxazolidines as anti-bacterial agents ALPI, HLA-A, HLA-B NR3C2 2377/4885PGR 4796/4885NR3C1 3666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.