Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279667 | 0.88 | MEN1 (0.49) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL15451360 | 0.87 | MEN1 (0.43) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL8399191 | 0.85 | MEN1 (0.48) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| Hydrochloric Acid SCHEMBL31131863 | 0.84 | MEN1 (0.45) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL7722774 | 0.83 | MEN1 (0.52) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL14016347 | 0.82 | MEN1 (0.46) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL1026522 | 0.80 | MEN1 (0.44) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL2410161 | 0.80 | MMP8 (0.49) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL18290151 | 0.80 | MEN1 (0.68) | ALDH1A1MEN1KMT2ATSHRCYP4F2 | |
| SCHEMBL7709450 | 0.80 | MEN1 (0.49) | ALDH1A1MEN1KMT2ATSHRCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |