Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15451360 | 0.93 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL15437899 | 0.87 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2638021 | 0.87 | MMP8 (0.43) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL28512089 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL28464690 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4382740 | 0.84 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL1963 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4380430 | 0.82 | MEN1 (0.36) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4377134 | 0.82 | MMP8 (0.36) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL15437624 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013121018-A1 | SYNTHESIS OF CYANOCARBOXYLIC ACID ALKYL ESTERS | LONZA LTD (CH) | 2013-08-22 | — | — | WO | disclosed |
| WO-2013121017-A1 | PROCESS AND EQUIPMENT FOR THE PREPARATION OF HALOCARBOXYLIC ACID ALKYL ESTERS | LONZA LTD (CH) | 2013-08-22 | — | — | WO | disclosed |
| US-7435831-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435831-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435830-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435830-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| WO-2007027734-A2 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX, INC. (US) | 2007-03-08 | — | — | WO | disclosed |