Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | CASP3 | P42574 | 4/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550678 | 1.00 | KDM4E (0.63) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL1549478 | 0.98 | KDM4E (0.61) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL802768 | 0.88 | HSD17B10 (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13866524 | 0.84 | ESR1 (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14148310 | 0.84 | RAB9A (0.73) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13866517 | 0.84 | TOP2A (0.62) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL802592 | 0.83 | MAPT (0.55) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL7053445 | 0.83 | KDM6B (0.61) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2243598 | 0.83 | MAPT (0.71) | KDM4ERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13620844 | 0.83 | KDM4E (0.69) | KDM4ERAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | claimed |
| JP-2012500235-A | — | — | 2012-01-05 | — | — | JP | claimed |
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | claimed |
| EP-2313383-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | Merck Patent GmbH (DE) | 2011-04-27 | — | — | EP | claimed |
| WO-2010020352-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | claimed |
| US-9601704-B2 | Organic light-emitting device and display apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-03-21 | — | — | US | disclosed |
| US-9466804-B2 | Organic light-emitting element | CANON KABUSHIKI KAISHA (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20150364703-A1 | ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-12-17 | — | — | US | disclosed |
| US-20150357587-A1 | ORGANIC LIGHT-EMITTING ELEMENT | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-12-10 | — | — | US | disclosed |
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| EP-2313383-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | Merck Patent GmbH (DE) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010020352-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020352-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | SLC25A21, SLCO4C1, SLCO1B3 | KDM4E 4607/4885RAB9A 1290/4885NPC1 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.