Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 8/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866517 | 0.89 | TOP2A (0.62) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL13866514 | 0.87 | TOP2A (0.60) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL18065795 | 0.84 | TOP2A (0.57) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL1550678 | 0.83 | KDM4E (0.63) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL196301 | 0.83 | KDM4E (0.63) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL802768 | 0.83 | HSD17B10 (0.60) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL13252869 | 0.82 | MAPT (0.56) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL12304268 | 0.82 | ESR1 (0.54) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL2244631 | 0.82 | RAB9A (0.58) | MAPTTP53KDM4ENPC1RAB9A | |
| SCHEMBL2245492 | 0.82 | MAPT (0.66) | MAPTTP53KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796684-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9796684-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9537105-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| US-9334260-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9334260-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9199972-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9199972-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-9126970-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9126970-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9040172-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-05-26 | — | — | US | disclosed |
| US-8679647-B2 | Organic electroluminescent device comprising triazine derivatives | MERCK PATENT GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130032764-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2013-02-07 | — | — | US | disclosed |
| US-20120228552-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120223276-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20120168735-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2012-07-05 | — | — | US | disclosed |
| US-20120097899-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110095282-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | MAPT 1399/4885TP53 4242/4885KDM4E 1899/4885 |
| US-20130032764-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TYMS, TYMP, NUDT1 | MAPT 1168/4885TP53 667/4885KDM4E 3436/4885 |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | MAPT 1399/4885TP53 4242/4885KDM4E 1899/4885 |
| US-20120097899-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, ICMT, NUDC | MAPT 1086/4885TP53 3917/4885KDM4E 3141/4885 |
| US-20110095282-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES | KCNJ2, IKZF2, TERT | MAPT 871/4885TP53 3466/4885KDM4E 2566/4885 |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | PIEZO1, EMC1, EPCAM | MAPT 1283/4885TP53 4482/4885KDM4E 3460/4885 |
| US-20120228552-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | ILK, VIM, NES | MAPT 820/4885TP53 2800/4885KDM4E 4231/4885 |
| US-20120223276-A1 | MATERIALS FOR ELECTRONIC DEVICES | ERCC1, XPOT, EMD | MAPT 1580/4885TP53 4474/4885KDM4E 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.