Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609370 | 0.98 | FAAH (0.46) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL6096573 | 0.96 | FAAH (0.43) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL6096574 | 0.96 | FAAH (0.43) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL11861443 | 0.93 | DNM1 (0.42) | FAAHTRPV1EPHX2DNM1TERT | |
| SCHEMBL29617185 | 0.89 | FAAH (0.46) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL29617198 | 0.89 | FAAH (0.46) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL29617184 | 0.86 | FAAH (0.43) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL16390314 | 0.86 | LMNA (0.44) | FAAHTRPV1MAPTBLMHSD17B10 | |
| SCHEMBL16390202 | 0.86 | LMNA (0.44) | FAAHTRPV1MAPTBLMHSD17B10 | |
| SCHEMBL16389886 | 0.86 | LMNA (0.44) | FAAHTRPV1MAPTBLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201342-A1 | POLYNUCLEOTIDES ENCODING JAGGED1 FOR THE TREATMENT OF ALAGILLE SYNDROME | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |