Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960574 | 0.90 | HDAC7 (0.33) | EPHX2CTSKCTSSTSHRCYP3A4 | |
| SCHEMBL7183665 | 0.82 | EPHX2 (0.41) | EPHX2CA2CA1MAPK1CTSK | |
| SCHEMBL1960314 | 0.82 | — | — | |
| SCHEMBL14659358 | 0.81 | EPHX2 (0.40) | EPHX2CA2CA1MAPK1CTSK | |
| SCHEMBL1573329 | 0.77 | FAAH (0.40) | EPHX2CA1LMNA | |
| SCHEMBL7699097 | 0.77 | FAAH (0.40) | EPHX2CA1LMNA | |
| SCHEMBL11774081 | 0.77 | TSHR (0.49) | EPHX2CA2CA1CTSKTSHR | |
| SCHEMBL6725478 | 0.74 | FAAH (0.47) | EPHX2CA2CA1MAPK1CTSK | |
| SCHEMBL2047356 | 0.73 | EPHX2 (0.35) | EPHX2TSHR | |
| SCHEMBL8965442 | 0.72 | TSHR (0.36) | EPHX2CTSKCTSSTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708563-B2 | Lubricating composition containing an antiwear agent | THE LUBRIZOL CORPORATION (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150267140-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | LUBRIZOL CORP (US) | 2015-09-24 | — | — | US | disclosed |
| US-8946135-B2 | Lubricating composition containing a nitrile compound | THE LUBRIZOL CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120309657-A1 | Lubricating Composition Containing an Antiwear Agent | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120309655-A1 | Lubricating Composition Containing a Nitrile Compound | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| EP-2513270-A1 | LUBRICATING COMPOSITION CONTAINING A NITRILE COMPOUND | The Lubrizol Corporation (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2513272-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | The Lubrizol Corporation (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075403-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | THE LUBRIZOL CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075401-A1 | LUBRICATING COMPOSITION CONTAINING A NITRILE COMPOUND | THE LUBRIZOL CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |