SCHEMBL7183665

SCHEMBL7183665

CCCCC(C#N)OC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.41
ALDH1A1 P00352 1/20 0.39
CA2 P00918 5/20 0.37
CA1 P00915 3/20 0.37
MAPK1 P28482 1/20 0.36
PRKCA P17252 2/20 0.36
CES1 P23141 1/20 0.35
CTSK P43235 3/20 0.35
CTSS P25774 1/20 0.35
TSHR P16473 2/20 0.34
FAAH O00519 1/20 0.34
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699097 0.94 FAAH (0.40) EPHX2ALDH1A1CA1PRKCAFAAH
SCHEMBL1573329 0.94 FAAH (0.40) EPHX2ALDH1A1CA1PRKCAFAAH
SCHEMBL8965442 0.90 TSHR (0.36) EPHX2ALDH1A1PRKCACTSKCTSS
SCHEMBL7175617 0.90 TSHR (0.36) EPHX2ALDH1A1PRKCACTSKCTSS
Benzene SCHEMBL8964846 0.85 SLC6A3 (0.34) EPHX2ALDH1A1CTSKCTSSTSHR
SCHEMBL14659358 0.82 EPHX2 (0.40) EPHX2ALDH1A1CA2CA1MAPK1
SCHEMBL1963044 0.82 EPHX2 (0.40) EPHX2CA2CA1MAPK1CTSK
SCHEMBL7177949 0.82 TSHR (0.34) EPHX2CTSKTSHRTRPV1
SCHEMBL7575626 0.82 TSHR (0.32) EPHX2TSHR
SCHEMBL6384305 0.82 ALDH1A1 (0.40) ALDH1A1CA2CA1MAPK1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128238-B2 Optical material and molded product thereof MITSUI CHEMICALS, INC. (JP) 2015-09-08 US disclosed
US-20130030136-A1 OPTICAL MATERIAL AND MOLDED PRODUCT THEREOF MITSUI CHEMICALS, INC. (JP) 2013-01-31 US disclosed
EP-0926134-B1 Processes for producing alpha-cyanohydrin esters and alpha-hydroxy acids DAICEL CHEM (JP) 2003-09-17 EP disclosed
US-6111128-A IN THE PRESENCE OF A METAL CATALYST, REACTING AN ENOL ESTER OF GIVEN FORMULA OR OXIME ESTER WITH A CARBONYL COMPOUND AND CYANOGENATION AGENT TO FORM AN ALPHA-CYANOHYDRIN ESTER WHICH IS HYDROLYZED TO FORM ALPHA-HYDROXY ACIDS; EFFICIENCY DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-08-29 US disclosed
EP-0926134-A2 Processes for producing alpha-cyanohydrin esters and alpha-hydroxy acids Daicel Chemical Industries, Ltd. (JP) 1999-06-30 EP disclosed