Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963044 | 0.90 | EPHX2 (0.40) | EPHX2TDP1CYP3A4TSHRCTSS | |
| SCHEMBL1960314 | 0.83 | — | — | |
| SCHEMBL7175617 | 0.82 | TSHR (0.36) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL8965442 | 0.82 | TSHR (0.36) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL14659615 | 0.80 | HDAC7 (0.33) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL22090181 | 0.80 | LMNA (0.34) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| Benzene SCHEMBL8964846 | 0.77 | SLC6A3 (0.34) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL3101475 | 0.76 | TSHR (0.39) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL528600 | 0.76 | ALDH1A1 (0.39) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL7183665 | 0.72 | EPHX2 (0.41) | EPHX2TSHRCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708563-B2 | Lubricating composition containing an antiwear agent | THE LUBRIZOL CORPORATION (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150267140-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | LUBRIZOL CORP (US) | 2015-09-24 | — | — | US | disclosed |
| US-8946135-B2 | Lubricating composition containing a nitrile compound | THE LUBRIZOL CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120309655-A1 | Lubricating Composition Containing a Nitrile Compound | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120309657-A1 | Lubricating Composition Containing an Antiwear Agent | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| EP-2513270-A1 | LUBRICATING COMPOSITION CONTAINING A NITRILE COMPOUND | The Lubrizol Corporation (US) | 2012-10-24 | — | — | EP | disclosed |
| EP-2513272-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | The Lubrizol Corporation (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075403-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | THE LUBRIZOL CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075401-A1 | LUBRICATING COMPOSITION CONTAINING A NITRILE COMPOUND | THE LUBRIZOL CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |