Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630880 | 0.91 | SLC6A4 (0.35) | SLC6A4 | |
| SCHEMBL26326411 | 0.90 | SLC6A4 (0.38) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL26326406 | 0.80 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL17793531 | 0.79 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL17793566 | 0.79 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL17793530 | 0.79 | SLC6A4 (0.46) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL17793529 | 0.78 | SLC6A4 (0.43) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL26325419 | 0.72 | SLC6A4 (0.48) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL17793574 | 0.72 | SLC6A4 (0.37) | SLC6A4OPRM1OPRK1 | |
| SCHEMBL19627131 | 0.70 | SLC6A4 (0.35) | SLC6A4OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334923-A1 | OPIOID RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334923-A1 | OPIOID RECEPTOR MODULATORS | OPRM1, OPRL1, OPRD1 | SLC6A4 323/4885OPRM1 1/4885OPRK1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.