Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | CPA2 | P48052 | 1/20 | 0.37 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998248 | 0.84 | SIRT6 (0.57) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL21566740 | 0.84 | SIRT6 (0.57) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL10050111 | 0.83 | SIRT6 (0.52) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL14363444 | 0.83 | SIRT6 (0.56) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL20435077 | 0.82 | SIRT6 (0.58) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL12749404 | 0.82 | SIRT6 (0.58) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL20435058 | 0.82 | SIRT6 (0.58) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL20196381 | 0.81 | SIRT6 (0.58) | SIRT6SIRT1TLR2CHRM2CHRM4 | |
| SCHEMBL919220 | 0.80 | FOLH1 (0.62) | SIRT6SIRT1TLR2CA1CA2 | |
| SCHEMBL726302 | 0.80 | SIRT6 (0.56) | SIRT6SIRT1TLR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201322-A1 | TREATMENT OF OSTEOARTHRITIS WITH GINGIPAIN BLOCKING AGENTS | Cortexyme, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |