Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | CPA2 | P48052 | 1/20 | 0.40 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435077 | 1.00 | SIRT6 (0.58) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL20435058 | 1.00 | SIRT6 (0.58) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL11896083 | 0.90 | SIRT6 (0.56) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL726302 | 0.90 | SIRT6 (0.56) | SIRT6SIRT1CA1CA2FOLH1 | |
| Hydrochloric Acid SCHEMBL7347980 | 0.89 | SIRT6 (0.55) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL20530 | 0.86 | FOLH1 (0.62) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL919220 | 0.86 | FOLH1 (0.62) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL20529 | 0.86 | FOLH1 (0.62) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL16771271 | 0.86 | FOLH1 (0.49) | SIRT6SIRT1CA1CA2FOLH1 | |
| SCHEMBL7294147 | 0.85 | SIRT6 (0.55) | SIRT6SIRT1CA1CA2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137765-A1 | TRANSITION-METAL CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS | ILLUMINA, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| EP-3327027-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-3327027-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-01-06 | — | — | EP | disclosed |
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-2780039-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2780039-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170216452-A1 | ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION | PFIZER INC. | 2017-08-03 | — | — | US | disclosed |
| WO-2017093845-A1 | ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION | PFIZER INC. (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20160213742-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2016-07-28 | — | — | US | disclosed |
| US-9249186-B2 | Cytotoxic peptides and antibody drug conjugates thereof | PFIZER INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9138486-B2 | Cytotoxic peptides and antibody drug conjugates thereof | PFIZER INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20140363452-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. | 2014-12-11 | — | — | US | disclosed |
| US-8828401-B2 | Cytotoxic peptides and antibody drug conjugates thereof | PFIZER INC. (US) | 2014-09-09 | — | — | US | disclosed |
| WO-2013152325-A1 | PLASMINOGEN-OXIDIZED PHOSPHOLIPIDS FOR THE DETECTION OF CARDIOVASCULAR DISEASES AND DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013072813-A2 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| US-20130129753-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-7915223-B2 | Antimicrobial agents | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2011-03-29 | — | — | US | disclosed |
| US-20090053167-A1 | C-, S- and N-glycosylation of peptides | NEOSE TECHNOLOGIES, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2008154286-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20070032428-A1 | Novel antimicrobial agents | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140363452-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | NGLY1, CD47, CD81 | SIRT6 3981/4885SIRT1 4802/4885CA1 985/4885 |
| US-20070032428-A1 | Novel antimicrobial agents | NOTUM, DAO, SLC11A2 | SIRT6 3076/4885SIRT1 3395/4885CA1 4459/4885 |
| US-20090053167-A1 | C-, S- and N-glycosylation of peptides | QPCT, PTMS, NGLY1 | SIRT6 1207/4885SIRT1 1199/4885CA1 1269/4885 |
| US-20160213742-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | FPR1, FPR3, FPR2 | SIRT6 4495/4885SIRT1 3816/4885CA1 3132/4885 |
| US-20130129753-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | NGLY1, CD47, CD81 | SIRT6 3981/4885SIRT1 4802/4885CA1 985/4885 |
| US-20170216452-A1 | ANTIBODIES AND ANTIBODY FRAGMENTS FOR SITE-SPECIFIC CONJUGATION | DNPEP, PA2G4, CD2BP2 | SIRT6 3694/4885SIRT1 4831/4885CA1 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.