Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645880 | 0.91 | PRKCA (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL18665302 | 0.91 | PRKCA (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL25067341 | 0.91 | PRKCA (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL21842864 | 0.91 | KDM4E (0.58) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL29323958 | 0.89 | MAPT (0.47) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL24372245 | 0.88 | LMNA (0.46) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL23314097 | 0.86 | DNM1 (0.48) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL23794921 | 0.86 | DNM1 (0.48) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL23314027 | 0.86 | DNM1 (0.48) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL19636523 | 0.86 | DNM1 (0.48) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201349-A1 | POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |