Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784380 | 0.87 | MAPT (0.46) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL1787928 | 0.87 | MAPT (0.46) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL1784382 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL25812009 | 0.81 | TP53 (0.43) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8459740 | 0.79 | MAPT (0.57) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL9579979 | 0.78 | ALDH1A1 (0.48) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL18594367 | 0.77 | ALDH1A1 (0.43) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL7169867 | 0.76 | MAPT (0.53) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL9914232 | 0.76 | HDAC7 (0.45) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL2649579 | 0.74 | MAOA (0.42) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246536-B2 | Functionalized highly syndiotactic polystyrene and preparation method thereof | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2019-04-02 | — | — | US | disclosed |
| US-20170335036-A1 | FUNCTIONALIZED HIGHLY SYNDIOTACTIC POLYSTYRENE AND PREPARATION METHOD THEREOF | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-23 | — | — | US | disclosed |