Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079903 | 0.88 | MAPT (0.46) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL27720523 | 0.85 | TP53 (0.46) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8375669 | 0.85 | CYP2A6 (0.55) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL7169867 | 0.83 | MAPT (0.53) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL11017739 | 0.83 | TRPA1 (0.57) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL10520096 | 0.83 | ESR2 (0.55) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL30500513 | 0.83 | NPC1 (0.53) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL9579979 | 0.82 | ALDH1A1 (0.48) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL21708360 | 0.82 | ALDH1A1 (0.48) | MAPTNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL3853520 | 0.82 | MAPT (0.47) | MAPTNPC1ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934237-A1 | TETRACYCLIC COMPOUND HAVING LATERAL HALOGEN SUBSTITUENT AND LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME | CHISSO CORPORATION (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998008792-A1 | TETRACYCLIC COMPOUND HAVING LATERAL HALOGEN SUBSTITUENT AND LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME | CHISSO CORPORATION (JP) | 1998-03-05 | — | — | WO | disclosed |