Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19615912 | 0.88 | KDM4C (0.61) | SRD5A2RAB9AKDM5AKDM4CKDM5B | |
| SCHEMBL19631956 | 0.88 | NR4A2 (0.55) | NR4A2NR4A1NR4A3SRD5A2MEN1 | |
| SCHEMBL19615897 | 0.86 | ALOX5 (0.50) | MEN1KMT2AALOX5NR1H4SMN1; SMN2 | |
| SCHEMBL19615650 | 0.86 | NR4A2 (0.52) | NR4A2NR4A1NR4A3SRD5A2MEN1 | |
| SCHEMBL6176980 | 0.83 | ALOX5 (0.56) | NR4A2NR4A1NR4A3SRD5A2ALOX5 | |
| SCHEMBL19615641 | 0.80 | PLA2G4B (0.54) | NR4A2NR4A1NR4A3SRD5A2MEN1 | |
| SCHEMBL389730 | 0.77 | MEN1 (0.67) | NR4A2NR4A1NR4A3SRD5A2MEN1 | |
| SCHEMBL19616535 | 0.77 | NR4A2 (0.56) | NR4A2KDM5AKDM4CKDM5BMAOB | |
| SCHEMBL4220632 | 0.76 | NR4A1 (0.72) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL19615722 | 0.76 | MMP13 (0.50) | NR4A2KDM5AKDM5BMAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |