SCHEMBL1963237

SCHEMBL1963237

O=C(O)C1CCC(C(=O)O)C1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.50
POLB P06746 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
APEX1 P27695 2/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
PMP22 Q01453 2/20 0.46
GMNN O75496 1/20 0.46
TFPI2 P48307 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
THPO P40225 1/20 0.46
SLC1A2 P43004 4/20 0.42
SLC1A1 P43005 2/20 0.42
GABRR2 P28476 1/20 0.42
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9782998 0.93 GABRR1 (0.50) GABRR1POLBTDP1APEX1KDM4E
SCHEMBL722221 0.93 GABRR1 (0.50) GABRR1POLBTDP1APEX1KDM4E
Acetic Acid SCHEMBL7138694 0.91 POLB (0.46) GABRR1POLBTDP1APEX1KDM4E
SCHEMBL8400202 0.88 KDM4E (0.44) POLBTDP1APEX1KDM4ELMNA
SCHEMBL1297964 0.88 PEPD (0.48) GABRR1POLBTDP1APEX1KDM4E
SCHEMBL9494071 0.88 GABRR1 (0.46) GABRR1POLBTDP1APEX1KDM4E
SCHEMBL6864216 0.87 GABRR1 (0.50) GABRR1POLBTDP1APEX1KDM4E
Hydrochloric Acid SCHEMBL2384923 0.84 GABRR1 (0.48) GABRR1POLBTDP1APEX1KDM4E
Hydrochloric Acid SCHEMBL2885177 0.84 GABRR1 (0.48) GABRR1POLBTDP1APEX1KDM4E
SCHEMBL28986143 0.83 GABRR1 (0.42) GABRR1POLBTDP1APEX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2398757-A1 METHOD FOR PRODUCING A FREE ACID FROM THE SALT THEREOF Evonik Degussa GmbH (DE) 2011-12-28 EP claimed
EP-2398758-A1 REACTIVE EXTRACTION OF FREE ORGANIC ACIDS FROM AMMONIUM SALTS THEREOF Evonik Degussa GmbH (DE) 2011-12-28 EP claimed
WO-2010094554-A1 METHOD FOR PRODUCING A FREE ACID FROM THE SALT THEREOF EVONIK DEGUSSA GMBH (DE) 2010-08-26 WO claimed
WO-2010094630-A1 REACTIVE EXTRACTION OF FREE ORGANIC ACIDS FROM AMMONIUM SALTS THEREOF EVONIK DEGUSSA GMBH (DE) 2010-08-26 WO claimed
US-20100210871-A1 Reactive Extraction of Free Organic Acids from the Ammonium Salts Thereof EVONIK DEGUSSA GMBH (DE) 2010-08-19 US claimed
CN-114790270-A Moisture-curable polyurethane hot-melt resin composition, cured product, and laminate DIC株式会社 2022-07-26 CN disclosed
US-9976011-B2 Polymer composites and fabrications thereof THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2018-05-22 US disclosed
US-20170152347-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORP (US) 2017-06-01 US disclosed
US-20150321996-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORPORATION 2015-11-12 US disclosed
US-9066972-B2 Amide dendrimer compositions GENZYME CORPORATION (US) 2015-06-30 US disclosed
US-8900560-B2 Amide dendrimer compositions GENZYME CORPORATION (US) 2014-12-02 US disclosed
US-20140235724-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2014-08-21 US disclosed
US-5455325-A Optically active phenoxypropionic esters BASF AKTIENGESELLSCHAFT (DE) 1995-10-03 US disclosed
US-5417882-A Data carriers and display elements BASF AKTIENGESELLSCHAFT (DE) 1995-05-23 US disclosed
US-5417884-A Containing a thiadiazole group BASF AKTIENGESELLSCHAFT (DE) 1995-05-23 US disclosed
EP-0630945-A1 Use of reticulated azo dyes in non-linear optics BASF Aktiengesellschaft (DE) 1994-12-28 EP disclosed
US-5350873-A Optically active phenoxypropionic esters BASF AKTIENGESELLSCHAFT (DE) 1994-09-27 US disclosed
EP-0583605-A1 Defined oligomeric liquid crystalline compounds with smectic liquid crystalline phases BASF Aktiengesellschaft (DE) 1994-02-23 EP disclosed
EP-0528268-A2 Optically active esters of phenoxypropionic acid BASF Aktiengesellschaft (DE) 1993-02-24 EP disclosed
EP-0504660-A2 Liquid crystal compounds BASF Aktiengesellschaft (DE) 1992-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235724-A1 AMIDE DENDRIMER COMPOSITIONS FABP2, PHOSPHO1, PAM GABRR1 2167/4885POLB 2395/4885TDP1 3877/4885
US-20100210871-A1 Reactive Extraction of Free Organic Acids from the Ammonium Salts Thereof CA2, HCN2, CA9 GABRR1 3656/4885POLB 2673/4885TDP1 4649/4885
US-20150321996-A1 AMIDE DENDRIMER COMPOSITIONS FABP2, PHOSPHO1, PAM GABRR1 2167/4885POLB 2395/4885TDP1 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.