SCHEMBL19632491

SCHEMBL19632491

CCCCOc1c(OC)cc(CO)cc1OC

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SLC6A5 Q9Y345 2/20 0.46
PTGS2 P35354 1/20 0.46
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
SRC P12931 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9124419 0.93 S1PR2 (0.48)
SCHEMBL20436811 0.90 S1PR2 (0.46)
SCHEMBL13598843 0.89 SMN1; SMN2 (0.45) ALOX15TSHRHSD17B10SLC6A5SMN1; SMN2
SCHEMBL12338366 0.86 HTR2A (0.50) SLC6A5PTGS2HTR2AHTR2CHTR2B
SCHEMBL2744248 0.85 TSHR (0.50) ALOX15TSHRHSD17B10PTGS2HTR2A
SCHEMBL1200676 0.84 THRA (0.44) HTR2BSMN1; SMN2
SCHEMBL8965944 0.83 HTR2A (0.62) ALOX15TSHRHSD17B10PTGS2HTR2A
SCHEMBL4291750 0.83 HSD17B10 (0.60) ALOX15TSHRHSD17B10SMN1; SMN2
SCHEMBL1201460 0.82 THRA (0.45) HTR2B
SCHEMBL4864512 0.82 THRA (0.45) HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM ORGANOFUEL SWEDEN AB (SE) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM CBR1, ADH1C, AOC2 ALOX15 1184/4885TSHR 4190/4885HSD17B10 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.