Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588717 | 0.80 | SIGMAR1 (0.55) | KDM4ELMNAALDH1A1 | |
| SCHEMBL23671492 | 0.79 | SIGMAR1 (0.56) | SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL5757616 | 0.78 | HRH3 (0.56) | KDM4EALDH1A1CYP3A4CYP2C19HRH3 | |
| SCHEMBL4094728 | 0.74 | KDM4E (0.87) | SMN1; SMN2KDM4EALDH1A1HRH3 | |
| SCHEMBL17888266 | 0.72 | CARM1 (0.60) | SMN1; SMN2GAAKDM4ELMNAALDH1A1 | |
| SCHEMBL17277592 | 0.72 | CARM1 (0.60) | SMN1; SMN2GAAKDM4ELMNAALDH1A1 | |
| SCHEMBL17888267 | 0.72 | CARM1 (0.60) | SMN1; SMN2GAAKDM4ELMNAALDH1A1 | |
| SCHEMBL21078331 | 0.71 | KDM4E (0.47) | SMN1; SMN2GAAKDM4ELMNAALDH1A1 | |
| SCHEMBL21622407 | 0.70 | L3MBTL1 (0.54) | KDM4EALDH1A1HRH3 | |
| SCHEMBL19226319 | 0.69 | KDM4E (0.46) | SMN1; SMN2GAAKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201187-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC (US) | 2017-11-23 | — | — | WO | disclosed |