Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633363 | 0.93 | TLR7 (0.44) | ADCY5TLR7HPRT1NUDT1CYP2C19 | |
| SCHEMBL19633306 | 0.80 | TLR7 (0.47) | TLR7NUDT1HSD17B10 | |
| SCHEMBL3924378 | 0.80 | PNP (0.44) | TLR7HPRT1NUDT1 | |
| SCHEMBL19633466 | 0.79 | TLR7 (0.47) | CSNK2A2CSNK2A1TLR7NUDT1 | |
| SCHEMBL3924384 | 0.79 | PNP (0.41) | TLR7HPRT1 | |
| SCHEMBL3931875 | 0.78 | EGFR (0.58) | TLR7NUDT1 | |
| SCHEMBL19633727 | 0.78 | YTHDC1 (0.54) | TLR7NUDT1 | |
| SCHEMBL4096883 | 0.77 | PNP (0.41) | TLR7HPRT1NUDT1 | |
| SCHEMBL19553577 | 0.77 | ADORA2A (0.51) | TK1 | |
| SCHEMBL3921865 | 0.77 | ADORA2A (0.55) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197624-A1 | PURINE-SCAFFOLD TLR7 LIGANDS AND CONJUGATE THEREOF | SHENZHEN HORNETCORN BIOTECHNOLOGY COMPANY,CO., LTD (CN) | 2017-11-23 | — | — | WO | disclosed |