Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19539669 | 0.91 | YTHDC1 (0.59) | YTHDC1TLR7NUDT1HDAC1HDAC4 | |
| SCHEMBL24366542 | 0.90 | TLR7 (0.62) | YTHDC1TLR7HDAC1HDAC4HDAC6 | |
| SCHEMBL13728532 | 0.88 | YTHDC1 (0.56) | YTHDC1TLR7NUDT1PDE4APDE4B | |
| SCHEMBL509407 | 0.87 | TLR7 (0.64) | YTHDC1TLR7NUDT1PDE4APDE4B | |
| SCHEMBL17154082 | 0.86 | TLR7 (0.52) | YTHDC1TLR7NUDT1PDE4APDE4B | |
| SCHEMBL16481581 | 0.86 | TLR7 (0.52) | TLR7NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL19539672 | 0.85 | TLR7 (0.49) | TLR7NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL7206653 | 0.85 | TLR7 (0.51) | TLR7NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL4425489 | 0.82 | TLR7 (0.59) | TLR7NUDT1 | |
| SCHEMBL31126376 | 0.82 | TLR7 (0.59) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197624-A1 | PURINE-SCAFFOLD TLR7 LIGANDS AND CONJUGATE THEREOF | SHENZHEN HORNETCORN BIOTECHNOLOGY COMPANY,CO., LTD (CN) | 2017-11-23 | — | — | WO | disclosed |