Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352099 | 0.83 | LMNA (0.41) | ALDH1A1KMT2ALMNACTSSCTSK | |
| SCHEMBL27756024 | 0.81 | SRC (0.42) | ALDH1A1KMT2ALMNAL3MBTL1ATM | |
| SCHEMBL1925703 | 0.81 | SRC (0.42) | ALDH1A1KMT2ALMNAL3MBTL1ATM | |
| SCHEMBL2599350 | 0.76 | LMNA (0.45) | ALDH1A1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL27696378 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10KMT2AGAA | |
| Hydrochloric Acid SCHEMBL3529730 | 0.74 | LMNA (0.44) | ALDH1A1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL27280434 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KMT2ALMNAGAA | |
| SCHEMBL1820943 | 0.74 | LMNA (0.46) | ALDH1A1KMT2ALMNA | |
| SCHEMBL4958199 | 0.73 | KMT2A (0.45) | ALDH1A1TSHRKMT2ALMNAMAPT | |
| SCHEMBL1963341 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509942-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071947-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |