Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696365 | 0.84 | MIF (0.36) | TSHRKMT2AELANECTSSCTSK | |
| SCHEMBL27696367 | 0.84 | MIF (0.36) | TSHRKMT2AELANECTSSCTSK | |
| SCHEMBL27817033 | 0.84 | MIF (0.36) | TSHRKMT2AELANECTSSCTSK | |
| SCHEMBL27791305 | 0.82 | APP (0.35) | ALDH1A1KMT2AMEN1ELANECTSS | |
| SCHEMBL27636817 | 0.82 | ATM (0.41) | ALDH1A1TSHRHSD17B10L3MBTL1KMT2A | |
| SCHEMBL6606388 | 0.82 | ATM (0.41) | ALDH1A1TSHRHSD17B10L3MBTL1KMT2A | |
| SCHEMBL1925699 | 0.82 | ATM (0.41) | ALDH1A1TSHRHSD17B10L3MBTL1KMT2A | |
| SCHEMBL1351309 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL27756021 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL27735384 | 0.78 | GPR119 (0.37) | ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509942-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071947-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |
| CN-101023079-B | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE | 2010-05-05 | — | — | CN | disclosed |
| CN-101023079-A | Substituted hydantoins for the treatment of cancer | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | CN | disclosed |
| CN-101006085-A | Substituted hydantoins | HOFFMANN LA ROCHE (CH) | 2007-07-25 | — | — | CN | disclosed |