Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622284 | 0.75 | CES2 (0.32) | POLBELANEADCY1ALDH1A1GAA | |
| SCHEMBL2622738 | 0.71 | NR1H2 (0.54) | POLBALDH1A1RAB9AGAASMN1; SMN2 | |
| SCHEMBL10864231 | 0.69 | CES1 (0.48) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10863561 | 0.69 | CES1 (0.48) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17323160 | 0.69 | GAA (0.38) | POLBALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL3293759 | 0.69 | AKR1C3 (0.39) | POLBELANEALDH1A1RAB9AGAA | |
| SCHEMBL1314540 | 0.68 | NR1H2 (0.37) | POLBALDH1A1RAB9AGAASMN1; SMN2 | |
| SCHEMBL6546163 | 0.68 | TSHR (0.40) | POLBELANEALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7077404 | 0.67 | HPGD (0.36) | POLBELANEALDH1A1RAB9AGAA | |
| SCHEMBL1776842 | 0.67 | HPGD (0.36) | POLBELANEADCY1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170811-A1 | DENTAL IMPRESSION MATERIAL | DENTSPLY DETREY GMBH (DE) | 2019-09-12 | — | — | WO | disclosed |
| WO-2017198843-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |