Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889156 | 0.77 | ALDH1A1 (0.35) | HPGDALDH1A1 | |
| SCHEMBL19633491 | 0.75 | POLB (0.40) | MCL1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL5889119 | 0.72 | CYP2C19 (0.34) | HPGDALDH1A1 | |
| SCHEMBL5889275 | 0.71 | NR1H2 (0.33) | POLBHPGDALDH1A1 | |
| SCHEMBL5889273 | 0.71 | NR1H2 (0.33) | POLBHPGDALDH1A1 | |
| SCHEMBL10863561 | 0.68 | CES1 (0.48) | CES2CES1ACHEKMT2AMEN1 | |
| SCHEMBL5889253 | 0.67 | CYP2C19 (0.37) | — | |
| SCHEMBL1357104 | 0.66 | MCL1 (0.45) | CES2CES1MCL1MAPTTSHR | |
| SCHEMBL10864231 | 0.64 | CES1 (0.48) | CES2CES1ACHEKMT2AMEN1 | |
| Benzoic Acid SCHEMBL28288098 | 0.64 | TSHR (0.47) | CES2CES1MCL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246002-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |