SCHEMBL7077404

SCHEMBL7077404

O[Si](O)(c1ccccc1)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.36
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
EPHX1 P07099 2/20 0.35
RAB9A P51151 4/20 0.34
EPHX2 P34913 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
POLB P06746 1/20 0.34
ELANE P08246 1/20 0.34
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MTOR P42345 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
THPO P40225 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776842 0.83 HPGD (0.36) HPGDALDH1A1GAANR1H2NR1H3
SCHEMBL7085983 0.77 ALDH1A1 (0.35) HPGDALDH1A1GAANR1H2NR1H3
SCHEMBL15915044 0.77 ALDH1A1 (0.35) HPGDALDH1A1GAANR1H2NR1H3
SCHEMBL2289405 0.75 HPGD (0.32) HPGDALDH1A1GAANR1H2NR1H3
SCHEMBL15914886 0.75 GAA (0.34) HPGDALDH1A1GAARAB9APOLB
SCHEMBL16326803 0.75 GAA (0.34) HPGDALDH1A1GAARAB9APOLB
SCHEMBL1317821 0.74 NOS1 (0.35) HPGDALDH1A1GAANR1H2NR1H3
SCHEMBL1313850 0.74 CYP19A1 (0.37) HPGDALDH1A1GAARAB9APOLB
SCHEMBL1776841 0.74 HPGD (0.36) HPGDALDH1A1GAAEPHX1RAB9A
SCHEMBL5034194 0.74 ALDH1A1 (0.33) HPGDALDH1A1GAANR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352715-B1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes CONOCOPHILLIPS CO (US) 2003-11-19 EP claimed
EP-1132130-B1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes CONOCOPHILLIPS CO (US) 2003-07-02 EP claimed
EP-1132130-A1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes PHILLIPS PETROLEUM COMPANY (US) 2001-09-12 EP claimed
US-5115053-A Aging, spray drying and adding a chromium compound to produce a polymerization catalyst for olefins PHILLIPS PETROLEUM COMPANY (US) 1992-05-19 US claimed
US-4981831-A NEUTRAL AND ALKALINE AGING PHILLIPS PETROLEUM COMPANY (US) 1991-01-01 US claimed
EP-0352715-A1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1990-01-31 EP claimed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US claimed
EP-1132130-B1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes CONOCOPHILLIPS CO (US) 2003-07-02 EP disclosed
EP-1132130-A1 Twice-aged porous inorganic oxides, catalysts, and polymerization processes PHILLIPS PETROLEUM COMPANY (US) 2001-09-12 EP disclosed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US disclosed