Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.39 |
| ▸ | MAOA | P21397 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633750 | 0.88 | MAOA (0.39) | MAOBMAOAGRM4 | |
| SCHEMBL19633857 | 0.88 | CYP4F2 (0.42) | MAOBMAOAGRM4 | |
| SCHEMBL19633683 | 0.87 | CYP3A4 (0.42) | MAOBMAOAGRM4 | |
| SCHEMBL19633645 | 0.84 | SLC6A2 (0.43) | MAOBMAOANPC1RAB9ABACE1 | |
| SCHEMBL19633559 | 0.79 | KDR (0.42) | MAOBNPC1RAB9A | |
| SCHEMBL19633762 | 0.76 | TUBB1 (0.43) | — | |
| SCHEMBL27969044 | 0.74 | MAOA (0.50) | MAOBMAOARAB9AGRM4 | |
| SCHEMBL14691662 | 0.72 | MAOB (0.67) | MAOBMAOANPC1RAB9ABACE1 | |
| SCHEMBL19633687 | 0.72 | ERBB2 (0.49) | NPC1RAB9A | |
| SCHEMBL7485904 | 0.72 | KDR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |