Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633646 | 0.84 | MAOB (0.39) | MAOAMAOBBACE1NPC1RAB9A | |
| SCHEMBL19633857 | 0.80 | CYP4F2 (0.42) | MAOAMAOBFFAR1GRM4 | |
| SCHEMBL19633750 | 0.80 | MAOA (0.39) | MAOAMAOBFFAR1GRM4 | |
| SCHEMBL19633683 | 0.79 | CYP3A4 (0.42) | MAOAMAOBGRM4 | |
| SCHEMBL27969044 | 0.76 | MAOA (0.50) | MAOAMAOBRAB9AFFAR1GRM4 | |
| SCHEMBL19633687 | 0.72 | ERBB2 (0.49) | NPC1RAB9A | |
| SCHEMBL7488299 | 0.72 | NCF1 (0.56) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL28049941 | 0.69 | MAOA (0.50) | MAOAMAOBFFAR1 | |
| SCHEMBL7075105 | 0.68 | NPC1 (0.53) | MAOAMAOBNPC1RAB9AFFAR1 | |
| SCHEMBL9712932 | 0.67 | POLB (0.61) | MAOBNPC1RAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |