Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633701 | 0.87 | PDGFRB (0.47) | TLR8HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL29878333 | 0.86 | CYP3A4 (0.58) | TLR8NPC1RAB9AMAOBCYP3A4 | |
| SCHEMBL3898712 | 0.86 | CYP3A4 (0.58) | TLR8NPC1RAB9AMAOBCYP3A4 | |
| SCHEMBL29362202 | 0.85 | HTR1A (0.58) | TLR8HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL201122 | 0.85 | HTR1A (0.58) | TLR8HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL19633749 | 0.84 | TUBB1 (0.54) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL29487151 | 0.83 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22960002 | 0.83 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24659412 | 0.81 | NPC1 (0.43) | TLR8HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL19633800 | 0.81 | MAOB (0.51) | RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |