Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633749 | 0.88 | TUBB1 (0.54) | CYP19A1CYP11B1CYP11B2EGFRALDH1A1 | |
| SCHEMBL19633702 | 0.87 | TLR8 (0.48) | CYP3A4RAB9AHTR1AADRA1DADRA1A | |
| SCHEMBL29878333 | 0.79 | CYP3A4 (0.58) | LMNACYP3A4HIF1ARAB9ACYP1A2 | |
| SCHEMBL3898712 | 0.79 | CYP3A4 (0.58) | LMNACYP3A4HIF1ARAB9ACYP1A2 | |
| SCHEMBL29487151 | 0.79 | MEN1 (0.51) | PDGFRBPDGFRAEGFRPDE10ARAB9A | |
| SCHEMBL22960002 | 0.79 | MEN1 (0.51) | PDGFRBPDGFRAEGFRPDE10ARAB9A | |
| SCHEMBL201122 | 0.78 | HTR1A (0.58) | EGFRLMNAMAPK1CYP1A2KCNH2 | |
| SCHEMBL29362202 | 0.78 | HTR1A (0.58) | EGFRLMNAMAPK1CYP1A2KCNH2 | |
| SCHEMBL8602761 | 0.77 | MAOA (0.46) | EGFRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19633699 | 0.76 | GAK (0.57) | PDGFRAEGFRHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |