Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633702 | 0.81 | TLR8 (0.48) | MAOBRAB9A | |
| SCHEMBL3898712 | 0.80 | CYP3A4 (0.58) | MAOBRAB9ALMNAMAOA | |
| SCHEMBL29878333 | 0.80 | CYP3A4 (0.58) | MAOBRAB9ALMNAMAOA | |
| SCHEMBL1885566 | 0.80 | HSD17B10 (0.50) | MAPTLMNA | |
| SCHEMBL12003929 | 0.79 | CTSV (0.50) | MAOBMAPTNPSR1RAB9ACA12 | |
| SCHEMBL28621039 | 0.75 | CA12 (0.76) | MAOBMAPTNPSR1RAB9ACA12 | |
| SCHEMBL11658094 | 0.74 | CA12 (0.66) | MAOBMAPTNPSR1RAB9ACA12 | |
| SCHEMBL22718882 | 0.74 | CA12 (0.66) | MAOBMAPTNPSR1RAB9ACA12 | |
| SCHEMBL19633701 | 0.74 | PDGFRB (0.47) | MAPTNPSR1RAB9AHPGDLMNA | |
| SCHEMBL19633706 | 0.73 | PDGFRA (0.57) | MAOBMAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |