Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154082 | 0.90 | TLR7 (0.52) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16481581 | 0.90 | TLR7 (0.52) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL509407 | 0.88 | TLR7 (0.64) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19539672 | 0.87 | TLR7 (0.49) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL822730 | 0.86 | TLR7 (0.53) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19633727 | 0.85 | YTHDC1 (0.54) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19539669 | 0.84 | YTHDC1 (0.59) | TLR7ADORA2AADORA1NUDT1 | |
| SCHEMBL12305232 | 0.84 | TLR7 (0.46) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3957806 | 0.83 | AXL (0.51) | TLR7ADORA2AADORA1NUDT1 | |
| SCHEMBL161753 | 0.83 | TLR7 (0.46) | TLR7PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |