Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668850 | 0.96 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL20238129 | 0.96 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL31010076 | 0.86 | KDM4E (0.70) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL15566396 | 0.84 | SOS1 (0.49) | ALDH1A1KMT2AMEN1KDM4ECXCR3 | |
| SCHEMBL16877154 | 0.84 | KMT2A (0.43) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL6796135 | 0.83 | KDM4E (0.71) | ALDH1A1KDM4ESMN1; SMN2HTTPOLB | |
| Hydrochloric Acid SCHEMBL23850500 | 0.82 | CXCR3 (0.65) | ALDH1A1KDM4ESMN1; SMN2CXCR3POLB | |
| SCHEMBL21794075 | 0.81 | KDM4E (0.74) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL30596568 | 0.81 | MEN1 (0.60) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL30596583 | 0.81 | KDM4E (0.74) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |