Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634256 | 0.89 | P2RX3 (0.37) | P2RX3MEN1KMT2AMAPTSTS | |
| SCHEMBL19634012 | 0.85 | PDE4B (0.41) | P2RX3MEN1KMT2AMAPTEPHX2 | |
| SCHEMBL19614233 | 0.85 | SCN8A (0.37) | P2RX3PRMT5CNR1DYRK1AEGFR | |
| SCHEMBL19634031 | 0.84 | STS (0.36) | P2RX3CNR1MEN1KMT2AMAPT | |
| SCHEMBL29447377 | 0.80 | CNR1 (0.41) | CNR1DYRK1ASTSALDH1A1 | |
| SCHEMBL29447346 | 0.80 | CNR1 (0.41) | CNR1DYRK1ASTSALDH1A1 | |
| SCHEMBL19631557 | 0.80 | CNR1 (0.41) | CNR1DYRK1ASTSALDH1A1 | |
| SCHEMBL19631765 | 0.80 | CNR1 (0.41) | CNR1DYRK1ASTSALDH1A1 | |
| SCHEMBL19634114 | 0.80 | SCN1A (0.37) | P2RX3MEN1KMT2AALDH1A1 | |
| SCHEMBL19627625 | 0.78 | SCN8A (0.37) | CNR1DYRK1ASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |